Mediation is a crucial element in the learning process, especially in a virtual environment,
whether it corresponds to formal, non-formal, or informal education. This paper aims to expose the
research on mediation and learning in virtual environments published between 2015 and 2020. A total
of 299 articles were identified that address the topic of mediation and learning in virtual environments
from different fields and approaches. The results that respond to the research questions are presented.
The study was carried out with the Web of Science (WOS) and Scopus databases, and inclusion
and exclusion criteria were applied to obtain the articles under study. The Systematic Literature
Mapping (SLM) method was used to answer questions raised for analysis. Information was extracted
from the articles regarding the method used, the most cited articles, geographical distribution of
the authors by country, the journals and impact factor, type of mediation, and finally, the trends
and spaces where mediation takes place. The results show studies tending toward technological
mediation and factors such as interaction, collaboration, communication, and discussion, among
others. The practical implications are oriented to show the mediating factor from the pedagogical
and technological perspectives and its contribution to achieve meaningful learning.