The present chapter provides an analysis of the possible applications of the TAM (Technology Acceptance Model) for the study of the mobile technology acceptance process at the higher education level, through a literature review on the state of the art. With this aim in mind, the chapter will start by presenting the theoretical principles of the TAM model and its evolution. After that, the authors will describe the state of the research on the topic, first within the field of education in general, to focus then on the university level, and finally on mobile learning specifically. Throughout the analysis, the most significant studies will be highlighted as an example. Lastly, the authors will provide some brief conclusions and proposals for future lines of research derived from the consulted literature.